Surgical treatment for monolobular Caroli's disease ‒ Report of a 30-year single center case series.

Details

Serval ID
serval:BIB_44168634E824
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Surgical treatment for monolobular Caroli's disease ‒ Report of a 30-year single center case series.
Journal
Bioscience trends
Author(s)
Yamaguchi T., Cristaudi A., Kokudo T., Uldry E., Demartines N., Halkic N.
ISSN
1881-7823 (Electronic)
ISSN-L
1881-7815
Publication state
Published
Issued date
19/09/2018
Peer-reviewed
Oui
Volume
12
Number
4
Pages
426-431
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Congenital intrahepatic bile duct dilatation (Caroli's disease) is a rare biliary disease. Although multiple reports exist describing its surgical treatment, relatively few have provided long-term follow-up. Prospective data about 25 cases of monolobular Caroli's disease, with liver resection between 1974 and 2016, were retrospectively analyzed. Patient demographics together with postoperative outcomes and long-term follow-up were assessed. Our 25-patient cohort (average age 53.4 years (range: 27-82)) included 20 cases with disease limited to the left lobe, and 5 to the right. The average time interval between first symptoms and final diagnosis was 5 years (range: 0-34 years). The surgical procedures included left lobectomy in 11 cases, left hepatectomy in 8 cases, right hepatectomy in 3, and sub-segmentectomy in 3 cases. Biliodigestive anastomosis was performed in 7 cases. Complications were observed in 3 patients (25%). Metachronous cholangiocarcinoma was observed in one single case, 10 years after initial operation. In conclusion, surgical treatment for monolobular Caroli's disease is effective, with good short-term results and few complications. Median long-term follow-up was 18 months (range: 3-132), with favorable clinical evolution in 96% of patients.
Keywords
Caroli's disease, liver resection, monolobular
Pubmed
Web of science
Open Access
Yes
Create date
03/09/2018 14:41
Last modification date
20/08/2019 14:48
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