Genomic encryption of digital data stored in synthetic DNA.

Details

Serval ID
serval:BIB_43671755DDDE
Type
Autre: use this type when nothing else fits.
Collection
Publications
Institution
Title
Genomic encryption of digital data stored in synthetic DNA.
Author(s)
Grass R.N., Heckel R., Dessimoz C., Stark W.J.
ISSN
1521-3773 (Electronic)
ISSN-L
1433-7851
Issued date
21/02/2020
Language
english
Notes
Publication types: Journal Article
Publication Status: aheadofprint
Abstract
Today, we can read human genomes and store digital data robustly in synthetic DNA. Here we report a strategy to intertwine these two technologies to enable the secure storage of valuable information in synthetic DNA, protected with personalized keys. We show that genetic short tandem repeats (STRs) contain sufficient entropy to generate strong encryption keys, and that only one technology, DNA sequencing, is required to simultaneously read key and data. Using this approach, we experimentally generated 80 bit strong keys from human DNA, and used such a key to encrypt 17kB of digital information stored in synthetic DNA. Finally, the decrypted information was recovered perfectly from a single massively parallel sequencing run.
Keywords
Next Generation Sequencing, STR profiles, Synthetic DNA, biometrics
Pubmed
Create date
23/01/2020 16:29
Last modification date
16/04/2020 6:26
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