Mucocutaneous papillomatous papules in Cowden's syndrome.

Details

Serval ID
serval:BIB_4348B05AD7AC
Type
Article: article from journal or magazin.
Collection
Publications
Title
Mucocutaneous papillomatous papules in Cowden's syndrome.
Journal
Clinical and Experimental Dermatology
Author(s)
Jornayvaz F.R., Philippe J.
ISSN
0307-6938 (Print)
ISSN-L
0307-6938
Publication state
Published
Issued date
2008
Volume
33
Number
2
Pages
151-153
Language
english
Notes
Publication types: Case Reports ; Journal Article ; ReviewPublication Status: ppublish
Abstract
Cowden syndrome (CS; also known as multiple hamartoma syndrome) is a rare autosomal dominant disorder characterized by multiple hamartomas and a high risk of development of thyroid, breast, endometrial and other cancers. The cardinal features of the disease, which often lead to diagnosis, include mucocutaneous papillomatous papules and trichilemmomas. Most affected people develop these characteristic lesions by the age of 20 years. Once diagnosed, gene identification can be offered to family members of affected patients. We report a case of the disease and briefly review the current literature.
Keywords
Adult, Age Factors, Female, Hamartoma Syndrome, Multiple/genetics, Hamartoma Syndrome, Multiple/pathology, Humans, Monitoring, Immunologic, PTEN Phosphohydrolase/genetics, PTEN Phosphohydrolase/metabolism, Papilloma/diagnosis, Papilloma/genetics, Precancerous Conditions/genetics, Precancerous Conditions/pathology, Thyroid Gland/pathology, Thyroid Gland/surgery, Thyroidectomy/methods, Treatment Outcome
Pubmed
Web of science
Create date
03/11/2015 12:34
Last modification date
20/08/2019 13:47
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