DDX21: The link between m6A and R-loops.

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Serval ID
serval:BIB_424674BF9C11
Type
Article: article from journal or magazin.
Collection
Publications
Institution
UNIL/CHUV
Title
DDX21: The link between m6A and R-loops.
Journal
Molecular cell
Author(s)
Lavergne G., Roignant J.Y.
ISSN
1097-4164 (Electronic)
ISSN-L
1097-2765
Publication state
Published
Issued date
02/05/2024
Peer-reviewed
Oui
Volume
84
Number
9
Pages
1631-1632
Language
english
Notes
Publication types: Journal Article ; Comment
Publication Status: ppublish
Abstract
In this issue of Molecular Cell, Hao et al. <sup>1</sup> demonstrate that the RNA helicase DDX21 recruits the m <sup>6</sup> A methyltransferase complex to R-loops, ensuring proper transcription termination and genome stability.
Keywords
DEAD-box RNA Helicases/metabolism, DEAD-box RNA Helicases/genetics, Humans, R-Loop Structures, Methyltransferases/metabolism, Methyltransferases/genetics, Genomic Instability, Adenosine/metabolism, Adenosine/analogs & derivatives, Transcription Termination, Genetic
OAI-PMH
oai:serval.unil.ch:BIB_424674BF9C11
DOI
10.1016/j.molcel.2024.04.005
Pubmed
38701738
Web of science
001292557400001
Create date
10/05/2024 14:32
Last modification date
31/10/2024 7:13
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