Morphology of corticothalamic terminals arising from the auditory cortex of the rat: a Phaseolus vulgaris-leucoagglutinin (PHA-L) tracing study

Details

Serval ID
serval:BIB_41067F7B5D6D
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Morphology of corticothalamic terminals arising from the auditory cortex of the rat: a Phaseolus vulgaris-leucoagglutinin (PHA-L) tracing study
Journal
Hearing Research
Author(s)
Rouiller  E. M., Welker  E.
ISSN
0378-5955 (Print)
Publication state
Published
Issued date
11/1991
Volume
56
Number
1-2
Pages
179-90
Notes
Journal Article
Research Support, Non-U.S. Gov't --- Old month value: Nov
Abstract
Phaseolus vulgaris-leucoagglutinin (PHA-L) injection in the auditory cortex of the rat labeled anterogradely corticothalamic axons whose trajectory, morphology of terminals and their distribution were analyzed in light microscopy. From the primary auditory cortex, corticofugal axons ran in a rostral direction in the white matter (external capsule), and reached the internal capsule by crossing the caudate putamen. Then, they turned caudally, crossed the reticular nucleus (RE) of the thalamus, where some of them were seen to give off collaterals, ramifying in the 'auditory sector' of RE. From RE, the parent corticofugal axons continued in a caudal and medial direction to enter in the medial geniculate body (MGB). Corticofugal axons from the auditory cortex gave rise to 2 distinct types of terminals in the thalamus. First, small boutons (about 1 micron in diameter) were observed in the ventral division of the MGB (v-MGB; the main auditory relay nucleus in the thalamus), in RE, in the lateral part of the posterior thalamic nucleus, in the dorsal division of the MGB (d-MGB), as well as occasionally in the medial division of the MGB. Giant terminals (5-10 microns in diameter) formed the second type of cortical terminals, only present in a restricted zone of the ventral portion of d-MGB. Both types of terminals were observed as boutons 'terminaux' and 'en passant'. The zone of termination in v-MGB and RE varied as a function of the site of cortical injection. The similarity in the morphology and distribution of the terminals of corticothalamic axons arising from the primary auditory cortex with those of the primary somatosensory cortex of the mouse is striking and points to the existence of a basic pattern of connectivity used in corticothalamic processing of sensory information in rodents.
Keywords
Animals Auditory Cortex/*anatomy & histology Auditory Pathways/anatomy & histology Axons/ultrastructure Female Geniculate Bodies/anatomy & histology Male Phytohemagglutinins Rats Somatosensory Cortex/anatomy & histology Thalamus/anatomy & histology
Pubmed
Web of science
Create date
24/01/2008 14:40
Last modification date
20/08/2019 13:40
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