Calcium, vitamin D and cardiovascular disease.

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State: Public
Version: author
Serval ID
serval:BIB_40E2B5671312
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Calcium, vitamin D and cardiovascular disease.
Journal
Kidney and Blood Pressure Research
Author(s)
Guessous Idris, Bochud Murielle, Bonny Olivier, Burnier Michel
ISSN
1423-0143 (Electronic)
ISSN-L
1420-4096
Publication state
Published
Issued date
2011
Peer-reviewed
Oui
Volume
34
Number
6
Pages
404-417
Language
english
Abstract
The relationship between calcium and cardiovascular diseases (CVD) has been explored for a long time. Studies exploring the effect of calcium intake or calcium supplementation on cardiovascular risk suggest that systolic blood pressure increases under low calcium intake and decreases with calcium supplementation. A lower calcium intake has been associated with an increased risk of stroke. However, the impact of calcium supplementation on stroke risk remains unclear. Calcium supplementation may increase the risk of myocardial infarction. The relationship between vitamin D and CVD has been explored more recently. Negative correlations between vitamin D levels and the risk of hypertension, myocardial infarction, and stroke have been reported in several observational studies. The effect of vitamin D supplementation on blood pressure is still unclear and no effect of vitamin D supplementation on coronary heart disease or stroke has been clearly demonstrated. There is a lack of randomized clinical trials primarily addressing the effect of these parameters on CVD. Therefore, the real impact of calcium and vitamin D on cardiovascular outcomes remains to be documented by appropriate experimental data.
Pubmed
Web of science
Open Access
Yes
Create date
23/06/2011 8:05
Last modification date
20/10/2020 10:12
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