Mate and fuse: how yeast cells do it.

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Ressource 1Download: BIB_40238B00BF6D.P001.pdf (1090.86 [Ko])
State: Public
Version: Final published version
Serval ID
serval:BIB_40238B00BF6D
Type
Article: article from journal or magazin.
Publication sub-type
Letter (letter): Communication to the publisher.
Collection
Publications
Institution
Title
Mate and fuse: how yeast cells do it.
Journal
Open Biology
Author(s)
Merlini L., Dudin O., Martin S.G.
ISSN
2046-2441 (Electronic)
ISSN-L
2046-2441
Publication state
Published
Issued date
2013
Peer-reviewed
Oui
Volume
3
Number
3
Pages
130008
Language
english
Abstract
Many cells are able to orient themselves in a non-uniform environment by responding to localized cues. This leads to a polarized cellular response, where the cell can either grow or move towards the cue source. Fungal haploid cells secrete pheromones to signal mating, and respond by growing a mating projection towards a potential mate. Upon contact of the two partner cells, these fuse to form a diploid zygote. In this review, we present our current knowledge on the processes of mating signalling, pheromone-dependent polarized growth and cell fusion in Saccharomyces cerevisiae and Schizosaccharomyces pombe, two highly divergent ascomycete yeast models. While the global architecture of the mating response is very similar between these two species, they differ significantly both in their mating physiologies and in the molecular connections between pheromone perception and downstream responses. The use of both yeast models helps enlighten both conserved solutions and species-specific adaptations to a general biological problem.
Pubmed
Web of science
Open Access
Yes
Create date
11/03/2013 23:13
Last modification date
20/08/2019 13:37
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