Traitement de l'hypertension artérielle chez le sujet obèse [Treatment of hypertension in obese patients].

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State: Public
Version: Final published version
License: CC BY-NC-ND 4.0
Serval ID
serval:BIB_3FE9878B136C
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Traitement de l'hypertension artérielle chez le sujet obèse [Treatment of hypertension in obese patients].
Journal
Revue Médicale Suisse
Author(s)
Comte-Perret S., Giusti V., Wuerzner G.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
11/09/2013
Peer-reviewed
Oui
Volume
9
Number
397
Pages
1622-1626
Language
french
Notes
Publication types: English Abstract ; Journal ArticlePublication Status: ppublish. pdf type: mise au point...
Abstract
Prevalence of obesity and hypertension has increased these last decades. Around 60 to 70% of the incidence of hypertension is related to obesity. The relationship between obesity and hypertension is now well established. The sympathetic nervous system and the renin-angiotensin-aldosterone (RAA) system are activated in obese patients, mostly by insulin, and predispose the kidney to reabsorb sodium and water. In obese patients with hypertension, it is recommended to target a blood pressure < 140/90 mmHg. Lifestyle changes (weight loss, physical activity, low-salt diets) are useful to decrease blood pressure but are difficult to maintain in the long-term. When drugs are necessary, drugs that are metabolically neutral should be used, and often need to be combined to other drug classes in order to achieve blood pressure target.
Keywords
Blood Pressure/physiology, Humans, Hypertension/etiology, Hypertension/physiopathology, Incidence, Insulin/metabolism, Life Style, Obesity/complications, Obesity/physiopathology, Prevalence, Renin-Angiotensin System/physiology, Sympathetic Nervous System/metabolism
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Create date
23/12/2013 15:43
Last modification date
26/11/2024 7:11
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