Antiplaquettaires et hémorragie peropératoire. [Antiplatelet drugs and intraoperative hemorrhage]
Details
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State: Public
Version: Final published version
License: CC BY-NC-ND 4.0
State: Public
Version: Final published version
License: CC BY-NC-ND 4.0
Serval ID
serval:BIB_3F3D3FF38B59
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Antiplaquettaires et hémorragie peropératoire. [Antiplatelet drugs and intraoperative hemorrhage]
Journal
Revue Médicale Suisse
ISSN
1660-9379 (Print)
Publication state
Published
Issued date
22/11/2006
Peer-reviewed
Oui
Volume
2
Number
88
Pages
2684-7
Language
french
Notes
English Abstract
Journal Article
Review --- Old month value: Nov 22
Journal Article
Review --- Old month value: Nov 22
Abstract
Antiplatelet drugs and intraoperative haemorrhage Current literature demonstrates that there is less risk involved in maintaining anti-aggregant therapy (which might imply to transfuse more the patients), than in stopping it, which then increases dangerously the risk of coronary thrombosis. Aspirin, as a secondary preventive drug, should not be interrupted. Clopidogrel is essential for protection against thrombosis in areas where the endothelium is not intact. Unless there is a high hemorrhagic risk in closed cavities (intracranial surgery), clopidogrel should not be interrupted. Furthermore, any surgical intervention increasing the coagulability of the platelets, it seems particularly dangerous to stop such medication perioperatively.
Keywords
Algorithms Aspirin/*therapeutic use Blood Loss, Surgical/*physiopathology Coronary Thrombosis/*prevention & control Drug Therapy, Combination Humans Intraoperative Period Platelet Aggregation Inhibitors/*therapeutic use Platelet Glycoprotein GPIIb-IIIa Complex/antagonists & inhibitors Risk Assessment Ticlopidine/*analogs & derivatives/therapeutic use
Pubmed
Create date
28/01/2008 9:48
Last modification date
26/11/2024 7:10