Emerging Opportunities of Radiotherapy Combined With Immunotherapy in the Era of Breast Cancer Heterogeneity.

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State: Public
Version: Final published version
License: CC BY 4.0
Serval ID
serval:BIB_3F237867AE06
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Emerging Opportunities of Radiotherapy Combined With Immunotherapy in the Era of Breast Cancer Heterogeneity.
Journal
Frontiers in oncology
Author(s)
Tsoutsou P.G., Zaman K., Martin Lluesma S., Cagnon L., Kandalaft L., Vozenin M.C.
ISSN
2234-943X (Print)
ISSN-L
2234-943X
Publication state
Published
Issued date
2018
Peer-reviewed
Oui
Volume
8
Pages
609
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: epublish
Abstract
The association of radiotherapy and immunotherapy has recently emerged as an exciting combination that might improve outcomes in many solid tumor settings. In the context of breast cancer, this opportunity is promising and under investigation. Given the heterogeneity of breast cancer, it might be meaningful to study the association of radiotherapy and immunotherapy distinctly among the various breast cancer subtypes. The use of biomarkers, such as tumor infiltrating lymphocytes, which are also associated to breast cancer heterogeneity, might provide an opportunity for tailored studies. This review highlights current knowledge of the association of radiotherapy and immunotherapy in the setting of breast cancer and attempts to highlight the therapeutic opportunities among breast cancer heterogeneity.
Keywords
Cancer Research, Oncology, TILs, breast cancer, immunotherapy, radiotherapy, subtypes
Pubmed
Web of science
Open Access
Yes
Create date
03/01/2019 10:58
Last modification date
20/08/2019 13:36
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