Clinical Relevance and Characteristics of Aspergillus calidoustus and Other Aspergillus Species of Section Usti.

Details

Serval ID
serval:BIB_3E8FE6BF70D1
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Clinical Relevance and Characteristics of Aspergillus calidoustus and Other Aspergillus Species of Section Usti.
Journal
Journal of fungi
Author(s)
Glampedakis E., Erard V., Lamoth F.
ISSN
2309-608X (Electronic)
ISSN-L
2309-608X
Publication state
Published
Issued date
12/06/2020
Peer-reviewed
Oui
Volume
6
Number
2
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: epublish
Abstract
The Aspergilli of section Usti (group ustus) are represented by over 20 species, of which Aspergillus calidoustus is the most relevant human pathogen. Invasive aspergillosis (IA) caused by these fungi is rare but could represent an emerging issue among the expanding population of patients with long-term immunosuppression receiving antifungal prophylaxis. Clinicians should be aware of this unusual type of IA, which often exhibits distinct clinical features, such as an insidious and prolonged course and a high occurrence of extra-pulmonary manifestations, such as skin/soft tissue or brain lesions. Moreover, these Aspergillus spp. pose a therapeutic challenge because of their decreased susceptibility to azole drugs. In this review, we outline the microbiological and clinical characteristics of IA due to Aspergillus spp. of section Usti and discuss the therapeutic options.
Keywords
Aspergillus granulosus, Aspergillus insuetus, Aspergillus keveii, Aspergillus pseudodeflectus, Aspergillus puniceus, Aspergillus ustus, invasive aspergillosis
Pubmed
Open Access
Yes
Create date
25/06/2020 8:05
Last modification date
26/06/2020 6:26
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