T Cell-Mediated Immunity in the Immunosenescence Process

Details

Serval ID
serval:BIB_3E6D7C47FFAC
Type
A part of a book
Publication sub-type
Chapter: chapter ou part
Collection
Publications
Title
T Cell-Mediated Immunity in the Immunosenescence Process
Title of the book
Immunology of Aging
Author(s)
Lang PO.
Publisher
Springer
ISBN
978-3-642-39494-2
Publication state
Published
Issued date
2013
Editor
Rezaei N, Maasoud A.
Pages
161-176
Language
english
Abstract
Immunosenescence contributes to render older adults more susceptible to pathogens and to develop main age-related diseases. With the ever-increasing rise in the number and proportion of older persons worldwide, one of the challenges of a "long-life society" is to ensure that the years gained are not only healthy and disability-free years but also offering a good quality of life. In this perspective, recent research has concentrated on identifying the factors hindering healthy ageing, and among them, the age-related changes of the immune system have thus been particularly investigated. With respect to its central role in orchestrating the immune response, this chapter describes the main features of T cell-mediated immune senescence and the underlying mechanisms contributing to this state of increased vulnerability. Furthermore, it will explore the means by which T cell functions could be identified by using biomarkers.
Create date
15/04/2015 13:04
Last modification date
20/08/2019 13:35
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