Inversions are bigger on the X chromosome

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Serval ID
serval:BIB_3E55188717AD
Type
Article: article from journal or magazin.
Collection
Publications
Title
Inversions are bigger on the X chromosome
Journal
Molecular Ecology
Author(s)
Cheng Changde, Kirkpatrick Mark
ISSN
0962-1083
1365-294X
Publication state
Published
Issued date
03/2019
Volume
28
Number
6
Pages
1238-1245
Language
english
Abstract
In many insects, X‐linked inversions fix at a higher rate and are much less polymorphic
than autosomal inversions. Here, we report that in Drosophila, X‐linked inversions
also capture 67% more genes. We estimated the number of genes captured
through an approximate Bayesian computational analysis of gene orders in nine species
of Drosophila. X‐linked inversions fixed with a significantly larger gene content.
Further, X‐linked inversions of intermediate size enjoy highest fixation rate, while
the fixation rate of autosomal inversions decreases with size. A less detailed analysis
in Anopheles suggests a similar pattern holds in mosquitoes. We develop a population
genetic model that assumes the fitness effects of inversions scale with the
number of genes captured. We show that the same conditions that lead to a higher
fixation rate also produce a larger size for inversions on the X.
Keywords
Genetics, Ecology, Evolution, Behavior and Systematics
Pubmed
Web of science
Funding(s)
Swiss National Science Foundation / Projects
Create date
04/10/2019 15:44
Last modification date
05/10/2019 6:08
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