Fibre intake and laryngeal cancer risk

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Serval ID
serval:BIB_3E0F6CCC22FE
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Fibre intake and laryngeal cancer risk
Journal
Annals of Oncology
Author(s)
Pelucchi  Claudio, Talamini  Renato, Levi  Fabio, Bosetti  Cristina, La Vecchia  Carlo, Negri  Eva, Parpinel  Maria, Franceschi  Silvia
ISSN
0923-7534
Publication state
Published
Issued date
2003
Volume
14
Number
1
Pages
162-167
Notes
Réf. IUMSP: R 03/08
Type de document : Multicenter Studies
SAPHIRID:44950
Abstract
BACKGROUND: Consumption of vegetables, fruit and whole grain cereals has been inversely related to laryngeal cancer risk. Among the potential protective agents found in these foods, information on dietary fibres and laryngeal cancer risk are scanty. PATIENTS AND METHODS: A multi-centric, hospital-based case-control study was conducted on 527 patients with squamous-cell carcinoma of the larynx and 1,297 non-neoplastic controls. Cases and controls, frequency matched by age, sex and study centre, were interviewed using a validated food frequency questionnaire. RESULTS: Compared with the lowest quintile of fibre intake, the odds ratios (ORs) for the highest quintile were 0.3 [95% confidence interval (CI) 0.2-0.4] for total fibre, 0.3 (95% CI 0.2-0.5) for soluble non-cellulose polysaccharides (NCP) and for total insoluble fibre, including cellulose (OR = 0.3, 95% CI 0.2-0.4) and insoluble NCP (OR = 0.4, 95% CI 0.3-0.7). The ORs were 0.2 (95% CI 0.1-0.4) for fibre from vegetables, 0.5 (95% CI 0.3-0.7) from fruit and 1.1 (95% CI 0.6-1.9) from grains. The inverse association observed was similar among different subsites of laryngeal cancer, and consistent across strata of various covariates. CONCLUSIONS: This study found a strong inverse association between fibre intake and laryngeal cancer risk, which points to fibre as one of the beneficial components of vegetables and fruit. [Authors]
Keywords
Carcinoma, Squamous Cell , Dietary Fiber , Laryngeal Neoplasms
Pubmed
Web of science
Open Access
Yes
Create date
06/03/2008 16:30
Last modification date
25/09/2019 7:09
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