Bone non-union after osteotomy in patients treated with methotrexate

Details

Serval ID
serval:BIB_3E018C74CED3
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Bone non-union after osteotomy in patients treated with methotrexate
Journal
Journal of Rheumatology
Author(s)
Gerster  J. C., Bossy  R., Dudler  J.
ISSN
0315-162X (Print)
Publication state
Published
Issued date
12/1999
Volume
26
Number
12
Pages
2695-7
Notes
Case Reports
Journal Article --- Old month value: Dec
Abstract
We describe 2 men with seronegative rheumatoid arthritis who presented non-union of bone after osteotomy of the tibia in one case and of a metatarsal bone in the second. Both patients were still being treated with oral low doses of methotrexate (MTX). After MTX was stopped, a prompt healing of the bone occurred. These observations suggest that MTX should be stopped temporarily in cases with delayed bone healing after surgery.
Keywords
Antirheumatic Agents/adverse effects/*contraindications Arthritis, Rheumatoid/drug therapy/radiography/*surgery Bony Callus/*drug effects/radiography Humans Male Metatarsal Bones/physiopathology/surgery Methotrexate/adverse effects/*contraindications Middle Aged *Osteotomy Tibia/physiopathology/surgery Treatment Outcome
Pubmed
Web of science
Create date
25/01/2008 9:32
Last modification date
20/08/2019 14:34
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