L'examen histologique et cytologique des biopsies bronchiques et pulmonaires transbronchiques aux differents stades de la sarcoidose endothoracique. [Histologic and cytologic examination of bronchus and transbronchial lung biopsies at different stages of intrathoracic sarcoidosis]

Details

Serval ID
serval:BIB_3DD6614CBCFC
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
L'examen histologique et cytologique des biopsies bronchiques et pulmonaires transbronchiques aux differents stades de la sarcoidose endothoracique. [Histologic and cytologic examination of bronchus and transbronchial lung biopsies at different stages of intrathoracic sarcoidosis]
Journal
Schweizerische Medizinische Wochenschrift
Author(s)
Leuenberger  P., Zellweger  J. P., Vejdovsky  R., Favez  G.
ISSN
0036-7672 (Print)
Publication state
Published
Issued date
01/1981
Volume
111
Number
3
Pages
98-101
Notes
Comparative Study
English Abstract
Journal Article --- Old month value: Jan 17
Abstract
The frequency of bronchial and parenchymal involvement was studied in 44 patients with intrathoracic sarcoidosis by means of histologic and cytologic analysis of bronchial and pulmonary biopsies taken through bronchofiberscope. Endoscopy showed mucosal hyperemia with or without superficial granules in 59% of cases. Bronchial granulomatosis was found in 50% of cases at stages 0 and I, in 38% at stage II and in 42% at stage III. Epithelioid granulomas were seen in lung parenchym in 63% of cases at stages 0 and I, in 90% at stage II and 73% at stage III. Cytologic examination of bronchial brushings and biopsy imprints showed epithelioid and/or giant cells in 47% of cases at stages 0 and I, in 70% at stage II and in 68% at stage III. Cytology is therefore very useful in patients presenting with a clinical and radiological picture compatible with sarcoidosis. Bronchial and transbronchial lung biopsies represent the method of choice for obtaining histologic confirmation of intrathoracic sarcoidosis at all stages.
Keywords
Biopsy Bronchi/pathology Humans Lung/pathology Lung Diseases/diagnosis/pathology Sarcoidosis/*diagnosis/pathology Thoracic Diseases/*diagnosis/pathology
Pubmed
Web of science
Create date
25/01/2008 10:50
Last modification date
20/08/2019 14:34
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