Le carcinome rectal: necessite de la radiotherapie dans l'elaboration du plan therapeutique. [Rectal cancer: need for radiotherapy in determining the treatment plan]

Details

Serval ID
serval:BIB_3C4EF0BEB776
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Le carcinome rectal: necessite de la radiotherapie dans l'elaboration du plan therapeutique. [Rectal cancer: need for radiotherapy in determining the treatment plan]
Journal
Helvetica Chirurgica Acta
Author(s)
Coucke  P. A., Bosset  J. F., Mirimanoff  R. O.
ISSN
0018-0181 (Print)
Publication state
Published
Issued date
09/1991
Volume
58
Number
3
Pages
345-58
Notes
English Abstract
Journal Article
Review --- Old month value: Sep
Abstract
Postoperative radiotherapy is highly effective in the prevention of local recurrence in rectal cancer. Nevertheless, the results remain disappointing for Locally Advanced Rectal Cancer. New approaches include introduction of chemotherapy to postoperative radiotherapy or combined radiotherapeutic treatment with preoperative irradiation, surgery and intraoperative irradiation, along with elective postoperative treatment in function of surgical and pathological data. Based on recent advances in radiobiology we are able to modify treatment parameters to enhance efficacy without increasing the toxicity. The reduction of dose per fraction, the application of radiosensitizers, the optimal protection of healthy tissue will increase the therapeutic ratio while keeping results constant or even reduce the incidence of local failure.
Keywords
Combined Modality Therapy Humans Neoplasm Recurrence, Local/pathology/*radiotherapy/*surgery Neoplasm Staging Rectal Neoplasms/pathology/*radiotherapy/*surgery
Pubmed
Web of science
Create date
24/01/2008 17:12
Last modification date
20/08/2019 13:32
Usage data