VIH: prévention, traitement et perspectives [Novelties in HIV prevention and treatment in 2019]

Details

Serval ID
serval:BIB_3AE0F0E2F530
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
VIH: prévention, traitement et perspectives [Novelties in HIV prevention and treatment in 2019]
Journal
Revue medicale suisse
Author(s)
Kampouri E., Papadimitriou-Olivgeris M., Calmy A., Ciuffi A., Cavassini M.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
15/01/2020
Peer-reviewed
Oui
Volume
16
Number
676-7
Pages
92-98
Language
french
Notes
Publication types: English Abstract ; Journal Article
Publication Status: ppublish
Abstract
This article reviews the novelties in the prevention and treatment of HIV infection as well as the perspectives for a potential cure. The PrEP is a key component in the prevention of infection and the control of the epidemic. In order to decrease long-term toxicities, two-drug antiretroviral regimens are being implemented. Long-acting injectable molecules show promising efficacy and safety and are long awaited for patients tired of taking daily pills. Concerning adverse events, the association between integrase inhibitors and weight gain as well as recent data on the safety of dolutegravir during pregnancy are presented. Finally, a second case of sustained virological suppression in a patient who received a stem cell transplant with a mutation of the co-receptor CCR5 was reported, renewing hopes for possible cure by gene therapy.
Pubmed
Create date
23/01/2020 15:11
Last modification date
28/01/2020 6:26
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