Rhumatotogie. Les coxibes augmentent-ils les risques cardiovasculaires [Rheumatology. Do coxibs pose a cardiovascular risk?]

Details

Serval ID
serval:BIB_3A5ADC39C93C
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Rhumatotogie. Les coxibes augmentent-ils les risques cardiovasculaires [Rheumatology. Do coxibs pose a cardiovascular risk?]
Journal
Revue Médicale Suisse
Author(s)
So A., de Goumoëns P.
ISSN
1660-9379
Publication state
Published
Issued date
2005
Volume
1
Number
2
Pages
168-172
Language
french
Abstract
There is ongoing controversy regarding the cardiovascular safety of coxibes. Inhibition of COX-2 may have a pro-coagulant effect though available data does not support a class effect in human use. In clinical practice, prudence with its prescription is recommended. In cases which require treatment beyond one week, the individual cardiovascular and gastrointestinal risks need to be assessed. If the risk is predominantly gastrointestinal, a COXIB is indicated. If the cardiovascular risk is major, then a classical NSAID with gastric protection may be more appropriate.
Keywords
Cardiovascular Diseases, Cyclooxygenase Inhibitors, Humans, Risk Factors
Pubmed
Create date
02/03/2009 14:24
Last modification date
20/08/2019 13:30
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