A new method for accurate in vivo mapping of human brain connections using microstructural and anatomical information.

Details

Serval ID
serval:BIB_3962E37A1734
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
A new method for accurate in vivo mapping of human brain connections using microstructural and anatomical information.
Journal
Science advances
Author(s)
Schiavi S., Ocampo-Pineda M., Barakovic M., Petit L., Descoteaux M., Thiran J.P., Daducci A.
ISSN
2375-2548 (Electronic)
ISSN-L
2375-2548
Publication state
Published
Issued date
07/2020
Peer-reviewed
Oui
Volume
6
Number
31
Pages
eaba8245
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: epublish
Abstract
Diffusion magnetic resonance imaging is a noninvasive imaging modality that has been extensively used in the literature to study the neuronal architecture of the brain in a wide range of neurological conditions using tractography. However, recent studies highlighted that the anatomical accuracy of the reconstructions is inherently limited and challenged its appropriateness. Several solutions have been proposed to tackle this issue, but none of them proved effective to overcome this fundamental limitation. In this work, we present a novel processing framework to inject into the reconstruction problem basic prior knowledge about brain anatomy and its organization and evaluate its effectiveness using both simulated and real human brain data. Our results indicate that our proposed method dramatically increases the accuracy of the estimated brain networks and, thus, represents a major step forward for the study of connectivity.
Pubmed
Web of science
Open Access
Yes
Create date
28/08/2020 8:34
Last modification date
06/04/2024 7:23
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