Small bowel involvement in Crohn's disease: a prospective comparison of wireless capsule endoscopy and computed tomography enteroclysis
Details
Serval ID
serval:BIB_3881CB9177E0
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Small bowel involvement in Crohn's disease: a prospective comparison of wireless capsule endoscopy and computed tomography enteroclysis
Journal
Gut
ISSN
0017-5749 (Print)
Publication state
Published
Issued date
03/2005
Volume
54
Number
3
Pages
369-73
Notes
Comparative Study
Evaluation Studies
Journal Article --- Old month value: Mar
Evaluation Studies
Journal Article --- Old month value: Mar
Abstract
BACKGROUND: Wireless capsule endoscopy (WCE) offers endoscopic access to the small bowel and may therefore change diagnostic and therapeutic strategies in small bowel diseases. AIM: The aim of this prospective study was to validate the gain in information and therapeutic impact of WCE in patients with Crohn's disease. METHODS: Fifty six consecutive patients with Crohn's disease underwent computed tomography (CT) enteroclysis, and if stenoses <10 mm were excluded, WCE was carried out. RESULTS: In 15 patients (27%), WCE could not be performed due to strictures detected by CT enteroclysis. From the other 41 patients, jejunal or ileal lesions were found in 25 patients by WCE compared with 12 by CT enteroclysis (p=0.004). This gain in information was mainly due to detection of small mucosal lesions such as villous denudation, aphthoid ulcerations, or erosions. Both methods were not significantly different in the detection of lesions in the terminal/neoterminal ileum (WCE 24 patients, CT enteroclysis 20 patients). Therapy was changed due to WCE findings in 10 patients. Consecutively, all of them improved clinically. CONCLUSIONS: Capsule endoscopy improves the diagnosis of small bowel Crohn's disease. This may have significant therapeutic impact.
Keywords
Adult
Capsules
Crohn Disease/*diagnosis/drug therapy/radiography
Endoscopy, Gastrointestinal/adverse effects/*methods
Female
Humans
Ileal Diseases/diagnosis/drug therapy/radiography
Jejunal Diseases/diagnosis/drug therapy/radiography
Male
Prospective Studies
Telemetry/adverse effects/*methods
Tomography, X-Ray Computed
Pubmed
Web of science
Open Access
Yes
Create date
25/01/2008 17:08
Last modification date
20/08/2019 14:27