An international Delphi consensus for pelvic stereotactic ablative radiotherapy re-irradiation.

Details

Serval ID
serval:BIB_3825294D9B35
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
An international Delphi consensus for pelvic stereotactic ablative radiotherapy re-irradiation.
Journal
Radiotherapy and oncology
Author(s)
Slevin F., Aitken K., Alongi F., Arcangeli S., Chadwick E., Chang A.R., Cheung P., Crane C., Guckenberger M., Jereczek-Fossa B.A., Kamran S.C., Kinj R., Loi M., Mahadevan A., Massaccesi M., Mendez L.C., Muirhead R., Pasquier D., Pontoriero A., Spratt D.E., Tsang Y.M., Zelefsky M.J., Lilley J., Dickinson P., Hawkins M.A., Henry A.M., Murray L.J.
ISSN
1879-0887 (Electronic)
ISSN-L
0167-8140
Publication state
In Press
Peer-reviewed
Oui
Volume
164
Pages
104-114
Language
english
Notes
Publication types: Journal Article
Publication Status: aheadofprint
Abstract
Stereotactic Ablative Radiotherapy (SABR) is increasingly used to treat metastatic oligorecurrence and locoregional recurrences but limited evidence/guidance exists in the setting of pelvic re-irradiation. An international Delphi study was performed to develop statements to guide practice regarding patient selection, pre-treatment investigations, treatment planning, delivery and cumulative organs at risk (OARs) constraints.
Forty-one radiation oncologists were invited to participate in three online surveys. In Round 1, information and opinion was sought regarding participants' practice. Guidance statements were developed using this information and in Round 2 participants were asked to indicate their level of agreement with each statement. Consensus was defined as ≥75% agreement. In Round 3, any statements without consensus were re-presented unmodified, alongside a summary of comments from Round 2.
Twenty-three radiation oncologists participated in Round 1 and, of these, 21 (91%) and 22 (96%) completed Rounds 2 and 3 respectively. Twenty-nine of 44 statements (66%) achieved consensus in Round 2. The remaining 15 statements (34%) did not achieve further consensus in Round 3. Consensus was achieved for 10 of 17 statements (59%) regarding patient selection/pre-treatment investigations; 12 of 13 statements (92%) concerning treatment planning and delivery; and 7 of 14 statements (50%) relating to OARs. Lack of agreement remained regarding the minimum time interval between irradiation courses, the number/size of pelvic lesions that can be treated and the most appropriate cumulative OAR constraints.
This study has established consensus, where possible, in areas of patient selection, pre-treatment investigations, treatment planning and delivery for pelvic SABR re-irradiation for metastatic oligorecurrence and locoregional recurrences. Further research into this technique is required, especially regarding aspects of practice where consensus was not achieved.
Keywords
Consensus, Pelvic Cancer, Re-Irradiation, Stereotactic Ablative Radiotherapy, Stereotactic Body Radiotherapy, Pelvic cancer, Re-irradiation, Stereotactic ablative radiotherapy, Stereotactic body radiotherapy
Pubmed
Web of science
Create date
04/10/2021 10:45
Last modification date
30/10/2021 5:36
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