Insuffisance rénale severe sur maladie des emboles de cholestérol: controverses thérapeutiques revisitées [Severe renal insufficiency secondary to renal cholesterol emboli: therapeutical options revisited]

Details

Serval ID
serval:BIB_37FDC60B93CF
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Insuffisance rénale severe sur maladie des emboles de cholestérol: controverses thérapeutiques revisitées [Severe renal insufficiency secondary to renal cholesterol emboli: therapeutical options revisited]
Journal
Revue Médicale Suisse
Author(s)
Simon R., Berwert L., Burnier M., Teta D.
ISSN
1660-9379[print], 1660-9379[linking]
Publication state
Published
Issued date
2010
Volume
6
Number
238
Pages
432-437
Language
french
Notes
Publication types: English Abstract ; Journal Article
Publication Status: ppublish
Abstract
Disseminated cholesterol crystal embolism is observed in elderly men with severe atherosclerosis. This syndrome may be triggered by arterial catheterizations, major vascular surgery, thrombolytic and/or anticoagulation treatment. Cutaneous signs, subacute renal insufficiency, a marked inflammatory syndrome and eosinophilia are common. Immunologic testing is normal except for hypocomplementaemia. The diagnosis may be confirmed by biopsy (skin, gastrointestinal or renal), and/or by a fundoscopic examination. The treatment consists in withdrawing all form of anticoagulation, proscribing vascular surgery and arterial catheterization, prescribing aspirin and statins, and controlling arterial blood pressure. Corticosteroids may be given in refractory cases. The prognosis of cholesterol crystal embolism is poor but may be improved by statins.
Keywords
Aged, Atherosclerosis/complications, Embolism, Cholesterol/complications, Embolism, Cholesterol/therapy, Humans, Male, Renal Insufficiency/etiology, Renal Insufficiency/therapy
Pubmed
Create date
24/06/2010 17:32
Last modification date
20/08/2019 13:26
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