Comparison between short- and long-term insulin-like growth factor response to recombinant human growth hormone

Details

Serval ID
serval:BIB_37C0AA92EC77
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Comparison between short- and long-term insulin-like growth factor response to recombinant human growth hormone
Journal
Hormone Research
Author(s)
Lopes  L. A., Theintz  G. E., Torresani  T., Sizonenko  P. C.
ISSN
0301-0163 (Print)
Publication state
Published
Issued date
1992
Volume
38
Number
5-6
Pages
245-9
Notes
Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Abstract
Eight growth-hormone-deficient children were treated with recombinant human GH (rhGH). Results of the short-term metabolic response to rhGH performed at the start of therapy during a 5-day introduction period and long-term results on growth were analyzed. We could not find any correlation between the effects on the short-term metabolic test and the growth response during long-term therapy, namely between the urea and insulin-like growth factor-I response during the short test and the increase in growth velocity. The short-term test is not a good predictor of the long-term response.
Keywords
Adolescent Blood Urea Nitrogen Body Height/drug effects Child Child, Preschool Female Growth/drug effects/physiology Growth Hormone/deficiency/*therapeutic use Humans Insulin-Like Growth Factor I/*metabolism Male Recombinant Proteins/therapeutic use Time Factors
Pubmed
Web of science
Create date
25/01/2008 10:30
Last modification date
20/08/2019 13:26
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