Réirradiation des tissus sains: données radiobiologiques précliniques [Reirradiation of normal tissues: preclinical radiobiological data]

Details

Serval ID
serval:BIB_37433F1AB1E8
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Réirradiation des tissus sains: données radiobiologiques précliniques [Reirradiation of normal tissues: preclinical radiobiological data]
Journal
Cancer radiotherapie
Author(s)
Bourgier C., Vozenin M.C., Deutsch E.
ISSN
1769-6658 (Electronic)
ISSN-L
1278-3218
Publication state
Published
Issued date
10/2010
Peer-reviewed
Oui
Volume
14
Number
6-7
Pages
412-415
Language
french
Notes
Publication types: English Abstract ; Journal Article ; Review
Publication Status: ppublish
Abstract
Reirradiation represent an unfrequent particular clinical situation. The risk/benefit ratio assessment must be taken into account, considering both clinical and dosimetric aspects. There is a relatively limited amount of preclinical data available to date and clinicians should cautiously perform reirradiations in selected indications. This review summarizes the experimental data available on reirradiation of normal tissues, the consequences on early and late toxicities as well as the intrinsic limitations of these models.

Keywords
Animals, Bone Marrow/radiation effects, Dose-Response Relationship, Radiation, Fibrosis, Haplorhini, Humans, Mice, Nervous System/radiation effects, Organ Specificity, Radiation Injuries/etiology, Radiation Injuries/physiopathology, Radiation Injuries/prevention & control, Radiation Injuries, Experimental/etiology, Radiation Injuries, Experimental/pathology, Radiation Tolerance, Radiotherapy/adverse effects, Radiotherapy/methods, Radiotherapy Dosage, Rats, Skin/radiation effects, Viscera/radiation effects
Pubmed
Web of science
Create date
30/04/2018 15:03
Last modification date
20/08/2019 13:25
Usage data