Infection screening in sudden and progressive idiopathic sensorineural hearing loss: a retrospective study of 182 cases

Details

Serval ID
serval:BIB_370BA9BD9B12
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Infection screening in sudden and progressive idiopathic sensorineural hearing loss: a retrospective study of 182 cases
Journal
Otology and Neurotology
Author(s)
Gagnebin  J., Maire  R.
ISSN
1531-7129 (Print)
Publication state
Published
Issued date
03/2002
Volume
23
Number
2
Pages
160-2
Notes
Journal Article --- Old month value: Mar
Abstract
OBJECTIVE: To evaluate a systematic infectious screening program for patients who present with sudden or progressive sensorineural hearing loss (SHL) of unknown cause (negative history and clinical examination). METHOD: Retrospective study of 182 patients with idiopathic SHL. One hundred six patients presented with sudden SHL, and 76 presented with progressive SHL. Serologies for herpes simplex and varicella-zoster viruses (immunoglobulin M and immunoglobulin G titers), Lyme disease (enzyme-linked immunosorbent assay), syphilis (fluorescent treponemal antibody absorption or microhemagglutination-Treponema pallidum test) and human immunodeficiency virus were performed. RESULTS: The serologies were negative in 179 patients. Two patients had positive serologies for Lyme disease and another tested positive for syphilis. Both cases of suspected Lyme disease were later excluded by Western blot analysis and lumbar puncture (two false-positives). The patient with serologic syphilis was diagnosed as having latent syphilis after neurosyphilis was excluded. CONCLUSION: The infection screening was positive in only 1 (0.6%) of 182 patients: the patient who was diagnosed with latent syphilis. On the basis of these results and taking into account the cost of systematic screening, we propose that serologic tests be limited to patients with suspect histories or symptomatologies, except for patients with a diagnosis of syphilis.
Keywords
Adolescent Adult Aged Aged, 80 and over Antibodies, Viral/immunology Blotting, Western Enzyme-Linked Immunosorbent Assay Female Hearing Loss, Sensorineural/*epidemiology/immunology/*virology Humans Male *Mass Screening Middle Aged Retrospective Studies Virus Diseases/*epidemiology/immunology/*virology
Pubmed
Web of science
Create date
25/01/2008 11:00
Last modification date
20/08/2019 13:25
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