Fetal breathing movements and lung hypoplasia: preliminary human observations

Details

Serval ID
serval:BIB_36CBA908A606
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Fetal breathing movements and lung hypoplasia: preliminary human observations
Journal
American Journal of Obstetrics and Gynecology
Author(s)
Fox  H. E., Moessinger  A. C.
ISSN
0002-9378 (Print)
Publication state
Published
Issued date
02/1985
Volume
151
Number
4
Pages
531-3
Notes
Journal Article
Research Support, U.S. Gov't, P.H.S. --- Old month value: Feb 15
Abstract
Hypoplasia of the fetal lung is found in association with long-standing oligohydramnios. In animal models, interference with fetal breathing activity has led to lung hypoplasia. It has been suggested that lung hypoplasia associated with oligohydramnios is due to inhibition of fetal breathing. Observations of seven patients with prolonged oligohydramnios, three of whom had lung hypoplasia, indicate that fetal breathing does occur in these cases and that is unlikely that lung hypoplasia is merely the result of absent fetal breathing activity. In fact, when compared to the four patients with oligohydramnios and presumably normal lungs, the three patients with oligohydramnios and lung hypoplasia spent more time breathing and did so at higher rates.
Keywords
Amniotic Fluid/physiology Female Fetal Movement Fetus/*physiology Humans Lung/*abnormalities/embryology Pregnancy Pregnancy Trimester, Third Respiration
Pubmed
Web of science
Create date
25/01/2008 13:16
Last modification date
20/08/2019 13:24
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