Factors associated with caregivers' underestimation of quality of life in patients with Alzheimer's disease.
Details
State: Public
Version: Final published version
License: Not specified
Serval ID
serval:BIB_364D168F05DB
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Factors associated with caregivers' underestimation of quality of life in patients with Alzheimer's disease.
Journal
Dementia and geriatric cognitive disorders
ISSN
1421-9824 (Electronic)
ISSN-L
1420-8008
Publication state
Published
Issued date
2012
Peer-reviewed
Oui
Volume
33
Number
1
Pages
11-17
Language
english
Notes
Publication types: Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Publication Status: ppublish
Abstract
The aim of this study was to identify the factors associated with differences between how Alzheimer's disease (AD) patients and their caregivers rate the patient's health-related quality of life (QoL).
Cross-sectional, multicentre study. Patients were 65 years or more, suffering from mild to moderate AD, native French speakers, with a main caregiver. Interrater agreement of the QoL-AD was assessed using the intraclass coefficient. A generalised linear model was used to identify factors related to the difference in health-related QoL scores between patients and their caregivers.
The 122 patients of the study were 82 ± 6 years old and mainly women (69%). Independent factors related to the difference between patients and caregivers were: Mini Mental State Exam score (β = 0.32; 95% CI = 0.05-0.59); instrumental activities of daily living score (β = -0.61; 95% CI = -1.14 to -0.07); total Neuropsychiatric Inventory score (β = 0.10; 95% CI = 0.05-0.59), and Zarit's burden score (β = 0.09; 95% CI = 0.01-0.17).
Practitioners must take into account the trend towards underestimation when health-related QoL is rated by caregivers or proxies.
Cross-sectional, multicentre study. Patients were 65 years or more, suffering from mild to moderate AD, native French speakers, with a main caregiver. Interrater agreement of the QoL-AD was assessed using the intraclass coefficient. A generalised linear model was used to identify factors related to the difference in health-related QoL scores between patients and their caregivers.
The 122 patients of the study were 82 ± 6 years old and mainly women (69%). Independent factors related to the difference between patients and caregivers were: Mini Mental State Exam score (β = 0.32; 95% CI = 0.05-0.59); instrumental activities of daily living score (β = -0.61; 95% CI = -1.14 to -0.07); total Neuropsychiatric Inventory score (β = 0.10; 95% CI = 0.05-0.59), and Zarit's burden score (β = 0.09; 95% CI = 0.01-0.17).
Practitioners must take into account the trend towards underestimation when health-related QoL is rated by caregivers or proxies.
Keywords
Activities of Daily Living, Aged, Aged, 80 and over, Alzheimer Disease/epidemiology, Alzheimer Disease/psychology, Alzheimer Disease/therapy, Caregivers/psychology, Cognition/physiology, Comorbidity, Cost of Illness, Data Interpretation, Statistical, Depression/complications, Depression/psychology, Educational Status, Female, France/epidemiology, Humans, Male, Neuropsychological Tests, Quality of Life, Sex Factors
Pubmed
Web of science
Create date
22/08/2024 23:04
Last modification date
23/08/2024 10:34
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