Individual quality of life is not correlated with health-related quality of life or physical function in patients with amyotrophic lateral sclerosis.

Details

Serval ID
serval:BIB_3610F87FCB55
Type
Article: article from journal or magazin.
Collection
Publications
Title
Individual quality of life is not correlated with health-related quality of life or physical function in patients with amyotrophic lateral sclerosis.
Journal
Journal of Palliative Medicine
Author(s)
Neudert C., Wasner M., Borasio G.D.
ISSN
1096-6218 (Print)
ISSN-L
1557-7740
Publication state
Published
Issued date
2004
Volume
7
Number
4
Pages
551-557
Language
english
Notes
Publication types: Journal ArticlePublication Status: ppublish
Abstract
We compared the change over time of individual quality of life (QOL) versus health-related QOL (HRQOL) and functional status in palliative care patients with amyotrophic lateral sclerosis (ALS). Forty-two patients with ALS performed the following assessments: the ALS functional rating scale (ALSFRS), the Sickness Impact Profile (SIP), the Short Form 36 (SF-36), and the Schedule for the Evaluation of Individual QOL-Direct Weighting (SEIQOL-DW). The SF-36 and the SEIQOL-DW were assigned at random. Patients were examined at least three times at 2-month intervals. There was a significant decrease from visit 1 to 3 (4-month period) in the function-based values of the SIP, SF-36, and ALSFRS. Despite this progressive decline of physical function and HRQOL, individual QOL as assessed by the SEIQOL-DW remained stable throughout the observation period. Correspondingly, there was a clear correlation between the ALSFRS, the SIP, and the SF-36, but no correlation between these scales and the SEIQOL-DW. The QOL domains most often named in the SEIQOL-DW were family, friends/social life, health, and profession. Thus, individual QOL appears to be largely independent from physical function in severely ill patients with ALS. Because of the characteristics of the scale, assessment of individual QOL may have an interventional value in palliative care.
Keywords
Activities of Daily Living, Adult, Aged, Amyotrophic Lateral Sclerosis/psychology, Disease Progression, Female, Germany, Health Status, Humans, Male, Middle Aged, Psychological Tests, Quality of Life, Statistics, Nonparametric
Pubmed
Create date
13/01/2014 17:27
Last modification date
20/08/2019 13:23
Usage data