Methodology used in studies reporting chronic kidney disease prevalence : a systematic literature review.

Details

Serval ID
serval:BIB_35D5BBF424F4
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Methodology used in studies reporting chronic kidney disease prevalence : a systematic literature review.
Journal
Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
Author(s)
Brück K., Jager K.J., Dounousi E., Kainz A., Nitsch D., Ärnlöv J., Rothenbacher D., Browne G., Capuano V., Ferraro P.M., Ferrieres J., Gambaro G., Guessous I., Hallan S., Kastarinen M., Navis G., Gonzalez A.O., Palmieri L., Romundstad S., Spoto B., Stengel B., Tomson C., Tripepi G., Völzke H., Wiȩcek A., Gansevoort R., Schöttker B., Wanner C., Vinhas J., Zoccali C., Van Biesen W., Stel V.S.
Working group(s)
European CKD Burden Consortium
Contributor(s)
Jousilahti P., Helmer C., Metzger M., Ruidavets JB., Bongard V., Koenig W., Denkinger MD., Brenner H., Saum KU., Nauck M., Stracke S., Perry I., Eustace J., Lupo A., Donfrancesco C., Palleschi S., Lamaida N., Capuano E., Sinkeler S., Wolffenbuttel BH., Bakker SJ., Aasarød K., Holmen J., Chudek J., Malgorzata M., Gardete-Correia L., Raposo£££João F£££ JF. , de Francisco AL. , Gayoso Diz P., Nerpin E., Lind L., Bochud M., Gaspoz JM., Fletcher A., Roderick P., Van Pottelbergh G., Van Der Tol A., Hadjadj S., Stojceva-Taneva O.
ISSN
1460-2385 (Electronic)
ISSN-L
0931-0509
Publication state
Published
Issued date
2015
Volume
30 Suppl 4
Pages
iv6-i16
Language
english
Notes
Publication types: Journal Article ; Review
Abstract
BACKGROUND: Many publications report the prevalence of chronic kidney disease (CKD) in the general population. Comparisons across studies are hampered as CKD prevalence estimations are influenced by study population characteristics and laboratory methods.
METHODS: For this systematic review, two researchers independently searched PubMed, MEDLINE and EMBASE to identify all original research articles that were published between 1 January 2003 and 1 November 2014 reporting the prevalence of CKD in the European adult general population. Data on study methodology and reporting of CKD prevalence results were independently extracted by two researchers.
RESULTS: We identified 82 eligible publications and included 48 publications of individual studies for the data extraction. There was considerable variation in population sample selection. The majority of studies did not report the sampling frame used, and the response ranged from 10 to 87%. With regard to the assessment of kidney function, 67% used a Jaffe assay, whereas 13% used the enzymatic assay for creatinine determination. Isotope dilution mass spectrometry calibration was used in 29%. The CKD-EPI (52%) and MDRD (75%) equations were most often used to estimate glomerular filtration rate (GFR). CKD was defined as estimated GFR (eGFR) <60 mL/min/1.73 m(2) in 92% of studies. Urinary markers of CKD were assessed in 60% of the studies. CKD prevalence was reported by sex and age strata in 54 and 50% of the studies, respectively. In publications with a primary objective of reporting CKD prevalence, 39% reported a 95% confidence interval.
CONCLUSIONS: The findings from this systematic review showed considerable variation in methods for sampling the general population and assessment of kidney function across studies reporting CKD prevalence. These results are utilized to provide recommendations to help optimize both the design and the reporting of future CKD prevalence studies, which will enhance comparability of study results.
Keywords
Adult, Biomarkers/analysis, Calibration, Europe/epidemiology, Glomerular Filtration Rate, Humans, Prevalence, Renal Insufficiency, Chronic/epidemiology, Renal Insufficiency, Chronic/physiopathology, Sampling Studies
Pubmed
Open Access
Yes
Create date
31/03/2016 14:58
Last modification date
20/08/2019 13:23
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