Adherence to the medical regime in patients with heart failure.

Details

Serval ID
serval:BIB_35D0861B581F
Type
Article: article from journal or magazin.
Collection
Publications
Title
Adherence to the medical regime in patients with heart failure.
Journal
European journal of heart failure
Author(s)
Muzzarelli S., Brunner-La Rocca H., Pfister O., Foglia P., Moschovitis G., Mombelli G., Stricker H.
ISSN
1879-0844 (Electronic)
ISSN-L
1388-9842
Publication state
Published
Issued date
04/2010
Peer-reviewed
Oui
Volume
12
Number
4
Pages
389-396
Language
english
Notes
Publication types: Clinical Trial ; Comparative Study ; Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Abstract
To assess adherence to medical treatment in patients with heart failure (HF) using a specific questionnaire and measurement of the serum concentration of digoxin.
Forty patients with symptomatic HF and a clinical indication for digoxin were included in this pilot study. The assessment of adherence to the medical regime was based on two different methods: (i) the CARDIA-Questionnaire and (ii) the measurement of serum digoxin concentration (SDC) at 1 and 6 months. All patients were placed on digoxin treatment (target SDC 0.6-0.8 ng/mL) at baseline. Poor adherence was defined if the patient self-reported taking < or =75% of the prescribed HF medication or had an SDC < 0.4 ng/mL (subtherapeutic range) at the follow-up visits. During the entire follow-up, the proportion of patients with poor adherence was 15% as assessed by the questionnaire, 20% as assessed by the SDC, and 25% if both methods were combined.
Although HF is a symptomatic disease, the proportion of patients with poor adherence to the medical regime in our study was high (up to 25%). The objective methodology based on the measurement of the SDC identified a higher number of patients with poor adherence when compared with the CARDIA-Questionnaire.
Keywords
Aged, Cardiotonic Agents/blood, Cardiotonic Agents/therapeutic use, Digoxin/blood, Digoxin/therapeutic use, Female, Health Behavior, Heart Failure/drug therapy, Humans, Male, Medication Adherence, Pilot Projects, Prospective Studies, Psychometrics, Risk Factors, Surveys and Questionnaires, Switzerland
Pubmed
Web of science
Open Access
Yes
Create date
15/11/2017 16:18
Last modification date
23/02/2024 14:09
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