Counting calories in Drosophila diet restriction.

Details

Serval ID
serval:BIB_35284997D1EF
Type
Article: article from journal or magazin.
Collection
Publications
Title
Counting calories in Drosophila diet restriction.
Journal
Experimental Gerontology
Author(s)
Min K.J., Flatt T., Kulaots I., Tatar M.
ISSN
0531-5565 (Print)
ISSN-L
0531-5565
Publication state
Published
Issued date
2007
Peer-reviewed
Oui
Volume
42
Number
3
Pages
247-251
Language
english
Abstract
The extension of life span by diet restriction in Drosophila has been argued to occur without limiting calories. Here we directly measure the calories assimilated by flies when maintained on full- and restricted-diets. We find that caloric intake is reduced on all diets that extend life span. Flies on low-yeast diet are long-lived and consume about half the calories of flies on high-yeast diets, regardless of the energetic content of the diet itself. Since caloric intake correlates with yeast concentration and thus with the intake of every metabolite in this dietary component, it is premature to conclude for Drosophila that calories do not explain extension of life span.
Keywords
Aging/physiology, Animal Nutritional Physiological Phenomena/physiology, Animals, Caloric Restriction/methods, Drosophila melanogaster/physiology, Energy Intake/physiology, Female, Larva/physiology, Longevity/physiology, Male, Yeasts
Pubmed
Web of science
Create date
28/01/2013 12:44
Last modification date
20/08/2019 13:22
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