Photodynamic therapy in the biliary tract.
Details
Serval ID
serval:BIB_3510CD971DA7
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Photodynamic therapy in the biliary tract.
Journal
Current Gastroenterology Reports
ISSN
1522-8037
Publication state
Published
Issued date
04/2001
Volume
3
Number
2
Pages
154-159
Language
english
Notes
Publication types: Journal Article ; Review
Abstract
Biliary tract cancers are rare malignancies usually characterized by slow growth and a low propensity for metastasis. Despite the relatively localized nature of these cancers, the only therapeutic measure with curative potential to date is surgical intervention. Because symptoms occur late, the diagnosis is rarely made at an early stage, and therefore only about half of the patients can have curative surgery. Patients with advanced disease face a dismal prognosis because palliative treatment options are limited. This review outlines recent advances in treatment of biliary cancer. Encouraging results from prospective, single-arm phase II trials of photodynamic therapy in nonresectable cholangiocarcinoma suggest considerable promise for this new palliative treatment modality. However, the apparent benefit of photodynamic therapy on survival, jaundice, and quality of life must be confirmed in a randomized multicenter trial.
Keywords
Bile Ducts, Extrahepatic/drug effects, Biliary Tract Neoplasms/drug therapy, Biliary Tract Neoplasms/epidemiology, Cholangiocarcinoma/drug therapy, Cholangiocarcinoma/epidemiology, Humans, Palliative Care, Photochemotherapy, Risk Factors, United States/epidemiology
Pubmed
Create date
25/01/2008 17:08
Last modification date
20/08/2019 14:22