STRING 8--a global view on proteins and their functional interactions in 630 organisms
Details
Download: 18940858_BIB_3463363DF111.pdf (3673.37 [Ko])
State: Public
Version: Final published version
License: CC BY-NC 4.0
State: Public
Version: Final published version
License: CC BY-NC 4.0
Serval ID
serval:BIB_3463363DF111
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
STRING 8--a global view on proteins and their functional interactions in 630 organisms
Journal
Nucleic Acids Research
ISSN
1362-4962 (Electronic)
ISSN-L
0305-1048
Publication state
Published
Issued date
2008
Volume
37
Number
Database issue
Pages
D412-D416
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Publication Status: ppublish
Abstract
Functional partnerships between proteins are at the core of complex cellular phenotypes, and the networks formed by interacting proteins provide researchers with crucial scaffolds for modeling, data reduction and annotation. STRING is a database and web resource dedicated to protein-protein interactions, including both physical and functional interactions. It weights and integrates information from numerous sources, including experimental repositories, computational prediction methods and public text collections, thus acting as a meta-database that maps all interaction evidence onto a common set of genomes and proteins. The most important new developments in STRING 8 over previous releases include a URL-based programming interface, which can be used to query STRING from other resources, improved interaction prediction via genomic neighborhood in prokaryotes, and the inclusion of protein structures. Version 8.0 of STRING covers about 2.5 million proteins from 630 organisms, providing the most comprehensive view on protein-protein interactions currently available. STRING can be reached at http://string-db.org/.
Keywords
Multiprotein Complexes/metabolism, Proteins/chemistry, Proteins/genetics, Proteins/metabolism
Pubmed
Web of science
Open Access
Yes
Create date
13/07/2018 10:00
Last modification date
20/08/2019 14:21