First evaluation of human sperm quality in various geographic regions of Switzerland

Details

Serval ID
serval:BIB_34458A75AE81
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
First evaluation of human sperm quality in various geographic regions of Switzerland
Journal
Chimia
Author(s)
Crausaz M., Vargas J., Parapanov R., Chollet Y., Wisard M., Stettler E., Senn A., Germond M.
ISSN
0009-4293
Publication state
Published
Issued date
2008
Peer-reviewed
Oui
Volume
62
Number
5
Pages
395-400
Language
english
Abstract
A decline in human sperm quality and quantity has been reported in numerous Western countries. This observation was also accompanied by an increase in urogenital malformations. The need for epidemiological studies dealing with unbiased populations in order to understand the causes of these observations is obvious. In Switzerland, the large majority of young men are asked to attend a military camp to be drafted into the army. A few weeks before this camp, conscripts were contacted and invited to participate in a large national study on semen quality. The participation was totally voluntary and anonymous. From September 2005 to June 2007, 770 volunteers filled out a questionnaire, underwent a clinical examination and provided sperm, blood and urine samples. Using self-rated health assessments, the observed cohort could be considered as healthy and no testicular cancer was found. Moreover, the testicular volumes, measured using Prader's orchidometry and ultrasonography, were comparable to those already published for young male populations. The median sperm concentration was 47 x 10(6)/ml, which is close to the concentration reported in Denmark, known to have the highest incidence of testicular cancer in Europe. Statistically significant differences were observed between regions with a lower sperm concentration for men residing in the Alps (43 x 10(6)/ml) and in the Zurich area (36 x 10(6)/ml) compared to men from West Plateau (54 x 10(6)/ml) and from the Jura (54 x 10(6)/ml). Such a regional discrepancy could be related to environmental factors, including endocrine disruptors. In order to confirm such regional differences more volunteers from the already studied regions should be studied and other parts of the country should be investigated. The rather low sperm concentration of Swiss young volunteers should be considered as a national health issue and investigated further.
Keywords
Casa, epidemiological study, sperm count, semen, Switzerland, Male Reproductive Health, Semen Quality, Juvenile Alligators, General-Population, European Countries, Control Lakes, Men, Abnormalities, Chemicals, Exposure
Web of science
Create date
14/10/2009 10:41
Last modification date
20/08/2019 13:20
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