Is chromatin remodeling required to build sister-chromatid cohesion?

Details

Serval ID
serval:BIB_33C8BE89ECE8
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Is chromatin remodeling required to build sister-chromatid cohesion?
Journal
Trends in Biochemical Sciences
Author(s)
Riedel C.G., Gregan J., Gruber S., Nasmyth K.
ISSN
0968-0004 (Print)
ISSN-L
0968-0004
Publication state
Published
Issued date
2004
Volume
29
Number
8
Pages
389-392
Language
english
Abstract
Chromosome segregation during mitosis and meiosis depends on the linkage of sister DNA molecules after replication. These links, known as sister-chromatid cohesion, are provided by a multi-subunit complex called cohesin. Recent papers suggest that chromatin-remodeling complexes also have a role in the generation of sister-chromatid cohesion. It remains unclear whether they do so by facilitating the recruitment of cohesin to specific chromosomal sequences or by modifying an event at replication forks giving rise to cohesion between sister DNAs.
Keywords
Animals, Chromatin, Chromatin Assembly and Disassembly, DNA Replication, Humans, Sister Chromatid Exchange/genetics, Sister Chromatid Exchange/physiology
Pubmed
Web of science
Create date
17/08/2016 10:56
Last modification date
03/03/2018 15:49
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