The perception of touch and the ventral somatosensory pathway.

Details

Ressource 1Download: serval:BIB_334F91BFC082.P001 (957.01 [Ko])
State: Public
Version: author
License: Not specified
It was possible to publish this article open access thanks to a Swiss National Licence with the publisher.
Serval ID
serval:BIB_334F91BFC082
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
The perception of touch and the ventral somatosensory pathway.
Journal
Brain : A Journal of Neurology
Author(s)
Preusser S., Thiel S.D., Rook C., Roggenhofer E., Kosatschek A., Draganski B., Blankenburg F., Driver J., Villringer A., Pleger B.
ISSN
1460-2156 (Electronic)
ISSN-L
0006-8950
Publication state
Published
Issued date
2015
Peer-reviewed
Oui
Volume
138
Number
Pt 3
Pages
540-548
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Abstract
In humans, touching the skin is known to activate, among others, the contralateral primary somatosensory cortex on the postcentral gyrus together with the bilateral parietal operculum (i.e. the anatomical site of the secondary somatosensory cortex). But which brain regions beyond the postcentral gyrus specifically contribute to the perception of touch remains speculative. In this study we collected structural magnetic resonance imaging scans and neurological examination reports of patients with brain injuries or stroke in the left or right hemisphere, but not in the postcentral gyrus as the entry site of cortical somatosensory processing. Using voxel-based lesion-symptom mapping, we compared patients with impaired touch perception (i.e. hypoaesthesia) to patients without such touch impairments. Patients with hypoaesthesia as compared to control patients differed in one single brain cluster comprising the contralateral parietal operculum together with the anterior and posterior insular cortex, the putamen, as well as subcortical white matter connections reaching ventrally towards prefrontal structures. This finding confirms previous speculations on the 'ventral pathway of somatosensory perception' and causally links these brain structures to the perception of touch.
Keywords
Adolescent, Adult, Aged, Brain Injuries/complications, Brain Injuries/pathology, Brain Mapping, Female, Functional Laterality/physiology, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging, Male, Middle Aged, Neural Pathways/pathology, Neurologic Examination, Perceptual Disorders/etiology, Perceptual Disorders/pathology, Somatosensory Cortex/pathology, Statistics, Nonparametric, Touch/physiology, Young Adult
Pubmed
Web of science
Open Access
Yes
Create date
04/01/2015 16:49
Last modification date
25/09/2019 6:08
Usage data