Improvement of the Contrast in Cancer Detection by Autofluorescence Bronchoscopy using a narrow spectral violet Excitation: A preliminary study

Details

Serval ID
serval:BIB_32BA28728930
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Improvement of the Contrast in Cancer Detection by Autofluorescence Bronchoscopy using a narrow spectral violet Excitation: A preliminary study
Journal
Biomedical Signal Processing and Control
Author(s)
Lovisa B., Gabrecht T., Andrejevic S., Grosjean P., Radu A., Monnier Ph., van den Bergh H., Wagnières G.
ISSN
1746-8094
Publication state
Published
Issued date
2007
Peer-reviewed
Oui
Volume
2
Number
3
Pages
234-38
Language
english
Abstract
Autofluorescence (AF) bronchoscopy is a useful tool for early cancer detection. However, the mechanisms involved in this diagnosis procedure are poorly understood. We present a clinical autofluorescence imaging study to assess the depth of the principal contrast mechanisms within the bronchial tissue comparing a narrowband (superficial) and broadband (penetrating) violet excitation. Knowledge of this parameter is crucial for the optimization of the spectral and optical design of clinical diagnostic AF imaging devices. An intensity contrast improvement was observed with the narrowband excitation, suggesting that the heme absorption plays a key role in the AF contrast mechanism.
Keywords
Medical systems Intensity contrast enhancement Autofluorescence imaging Bronchial cancer Clinical study
Web of science
Create date
14/12/2008 9:03
Last modification date
20/08/2019 13:18
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