Changes in the epidemiological landscape of invasive candidiasis.

Details

Serval ID
serval:BIB_32A16E1338F4
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Changes in the epidemiological landscape of invasive candidiasis.
Journal
The Journal of antimicrobial chemotherapy
Author(s)
Lamoth F., Lockhart S.R., Berkow E.L., Calandra T.
ISSN
1460-2091 (Electronic)
ISSN-L
0305-7453
Publication state
Published
Issued date
01/01/2018
Peer-reviewed
Oui
Volume
73
Number
suppl_1
Pages
i4-i13
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Review
Publication Status: ppublish
Abstract
The epidemiology of invasive candidiasis has evolved in recent years, warranting a review of the changes and the implications for current and future diagnosis and treatment. The overall burden of invasive candidiasis remains high, particularly in the expanding populations of patients at risk of opportunistic infection, such as the elderly or immunosuppressed. Progressive shifts from Candida albicans to non-albicans Candida spp. have been observed globally. The recent emergence of novel, multiresistant species, such as Candida auris, amplifies the call for vigilance in detection and advances in treatment. Among the current treatment options, fluconazole is still widely used throughout the world. Increased resistance to fluconazole, both acquired and naturally emerging, has been observed. Resistance to echinocandins is presently low but this may change with increased use. Improvement of diagnostic techniques and strategies, development of international surveillance networks and implementation of antifungal stewardship programmes represent major challenges for a better epidemiological control of invasive candidiasis.
Keywords
Antifungal Agents/therapeutic use, Antimicrobial Stewardship, Candida/classification, Candida/drug effects, Candida/isolation & purification, Candidiasis, Invasive/epidemiology, Candidiasis, Invasive/microbiology, Drug Resistance, Fungal, Epidemiological Monitoring, Global Health, Humans, Prevalence
Pubmed
Web of science
Open Access
Yes
Create date
22/01/2018 8:26
Last modification date
20/08/2019 13:18
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