Thyroid hormones regulate the formation and environmental plasticity of white bars in clownfishes.

Details

Serval ID
serval:BIB_3175D86F9AC6
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Thyroid hormones regulate the formation and environmental plasticity of white bars in clownfishes.
Journal
Proceedings of the National Academy of Sciences of the United States of America
Author(s)
Salis P., Roux N., Huang D., Marcionetti A., Mouginot P., Reynaud M., Salles O., Salamin N., Pujol B., Parichy D.M., Planes S., Laudet V.
ISSN
1091-6490 (Electronic)
ISSN-L
0027-8424
Publication state
Published
Issued date
2021
Peer-reviewed
Oui
Volume
118
Number
23
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Determining how plasticity of developmental traits responds to environmental conditions is a challenge that must combine evolutionary sciences, ecology, and developmental biology. During metamorphosis, fish alter their morphology and color pattern according to environmental cues. We observed that juvenile clownfish (Amphiprion percula) modulate the developmental timing of their adult white bar formation during metamorphosis depending on the sea anemone species in which they are recruited. We observed an earlier formation of white bars when clownfish developed with Stichodactyla gigantea (Sg) than with Heteractis magnifica (Hm). As these bars, composed of iridophores, form during metamorphosis, we hypothesized that timing of their development may be thyroid hormone (TH) dependent. We treated clownfish larvae with TH and found that white bars developed earlier than in control fish. We further observed higher TH levels, associated with rapid white bar formation, in juveniles recruited in Sg than in Hm, explaining the faster white bar formation. Transcriptomic analysis of Sg recruits revealed higher expression of duox, a dual oxidase implicated in TH production as compared to Hm recruits. Finally, we showed that duox is an essential regulator of iridophore pattern timing in zebrafish. Taken together, our results suggest that TH controls the timing of adult color pattern formation and that shifts in duox expression and TH levels are associated with ecological differences resulting in divergent ontogenetic trajectories in color pattern development.
Keywords
clownfishes, developmental plasticity, metamorphosis, pigmentation, thyroid hormones
Pubmed
Create date
31/05/2021 8:38
Last modification date
12/06/2021 6:34
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