Wet chemical silver treatment of endotracheal tubes to produce antibacterial surfaces.
Details
Serval ID
serval:BIB_31321E7BEA1E
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Wet chemical silver treatment of endotracheal tubes to produce antibacterial surfaces.
Journal
Journal of Biomedical Materials Research. Part B, Applied Biomaterials
ISSN
1552-4973[print], 1552-4973[linking]
Publication state
Published
Issued date
2007
Volume
83
Number
1
Pages
169-180
Language
english
Abstract
Mechanically ventilated patients in hospitals are subjected to an increased risk of acquiring nosocomial pneumonia that sometimes has a lethal outcome. One way to minimize the risk could be to make the surfaces on endotracheal tubes antibacterial. In this study, bacterial growth was inhibited or completely prevented by silver ions wet chemically and deposited onto the tube surface. Through the wet chemical treatment developed here, a surface precipitate was formed containing silver chloride and a silver stearate salt. The identity and morphology of the surface precipitate was studied using x-ray photoelectron spectroscopy, Fourier transform infrared spectroscopy, scanning electron microscopy, and x-ray powder diffraction. Leaching of silver ions into solution was examined, and bacterial growth on the treated surfaces was assayed using Pseudomonas aeruginosa wild type (PAO1) bacteria. Furthermore, the minimum inhibitory concentration of silver ions was determined in liquid- and solid-rich growth medium as 23 and 18 microM, respectively, for P. aeruginosa.
Keywords
Anti-Bacterial Agents/chemistry, Equipment Contamination/prevention & control, Humans, Intubation, Intratracheal/adverse effects, Ions/chemistry, Materials Testing, Molecular Structure, Pneumonia, Bacterial/etiology, Pneumonia, Bacterial/prevention & control, Pneumonia, Ventilator-Associated/prevention & control, Polyvinyl Chloride/chemistry, Pseudomonas Infections, Pseudomonas aeruginosa/metabolism, Respiration, Artificial/adverse effects, Salts/chemistry, Silver Compounds/chemistry, Surface Properties, Ventilators, Mechanical/microbiology
Pubmed
Web of science
Create date
25/01/2008 17:01
Last modification date
20/08/2019 13:16