Pregnancy and adolescence entail similar neuroanatomical adaptations: A comparative analysis of cerebral morphometric changes.

Details

Serval ID
serval:BIB_30F3320E40D6
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Pregnancy and adolescence entail similar neuroanatomical adaptations: A comparative analysis of cerebral morphometric changes.
Journal
Human brain mapping
Author(s)
Carmona S., Martínez-García M., Paternina-Die M., Barba-Müller E., Wierenga L.M., Alemán-Gómez Y., Pretus C., Marcos-Vidal L., Beumala L., Cortizo R., Pozzobon C., Picado M., Lucco F., García-García D., Soliva J.C., Tobeña A., Peper J.S., Crone E.A., Ballesteros A., Vilarroya O., Desco M., Hoekzema E.
ISSN
1097-0193 (Electronic)
ISSN-L
1065-9471
Publication state
Published
Issued date
05/2019
Peer-reviewed
Oui
Volume
40
Number
7
Pages
2143-2152
Language
english
Notes
Publication types: Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Abstract
Mapping the impact of pregnancy on the human brain is essential for understanding the neurobiology of maternal caregiving. Recently, we found that pregnancy leads to a long-lasting reduction in cerebral gray matter volume. However, the morphometric features behind the volumetric reductions remain unexplored. Furthermore, the similarity between these reductions and those occurring during adolescence, another hormonally similar transitional period of life, still needs to be investigated. Here, we used surface-based methods to analyze the longitudinal magnetic resonance imaging data of a group of 25 first-time mothers (before and after pregnancy) and compare them to those of a group of 25 female adolescents (during 2 years of pubertal development). For both first-time mothers and adolescent girls, a monthly rate of volumetric reductions of 0.09 mm <sup>3</sup> was observed. In both cases, these reductions were accompanied by decreases in cortical thickness, surface area, local gyrification index, sulcal depth, and sulcal length, as well as increases in sulcal width. In fact, the changes associated with pregnancy did not differ from those that characterize the transition during adolescence in any of these measures. Our findings are consistent with the notion that the brain morphometric changes associated with pregnancy and adolescence reflect similar hormonally primed biological processes.
Keywords
Adaptation, Physiological/physiology, Adolescent, Adult, Cerebral Cortex/diagnostic imaging, Cerebral Cortex/growth & development, Female, Humans, Magnetic Resonance Imaging/methods, Magnetic Resonance Imaging/trends, Organ Size/physiology, Pregnancy/physiology, Young Adult, MRI, adolescence, cortex, hormones, neuroanatomy, plasticity, pregnancy
Pubmed
Web of science
Open Access
Yes
Create date
31/01/2019 9:25
Last modification date
27/04/2020 5:20
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