Cell division ring, a new cell division protein and vertical inheritance of a bacterial organelle in anammox planctomycetes.

Details

Serval ID
serval:BIB_30A1F70737BD
Type
Article: article from journal or magazin.
Collection
Publications
Title
Cell division ring, a new cell division protein and vertical inheritance of a bacterial organelle in anammox planctomycetes.
Journal
Molecular Microbiology
Author(s)
van Niftrik L., Geerts W.J., van Donselaar E.G., Humbel B.M., Webb R.I., Harhangi H.R., Camp H.J., Fuerst J.A., Verkleij A.J., Jetten M.S., Strous M.
ISSN
1365-2958 (Electronic)
ISSN-L
0950-382X
Publication state
Published
Issued date
2009
Volume
73
Number
6
Pages
1009-1019
Language
english
Notes
Publication types: Journal ArticlePublication Status: ppublish
Abstract
Anammox bacteria are members of the phylum Planctomycetes that oxidize ammonium anaerobically and produce a significant part of the atmosphere's dinitrogen gas. They contain a unique bacterial organelle, the anammoxosome, which is the locus of anammox catabolism. While studying anammox cell and anammoxosome division with transmission electron microscopy including electron tomography, we observed a cell division ring in the outermost compartment of dividing anammox cells. In most Bacteria, GTP hydrolysis drives the tubulin-analogue FtsZ to assemble into a ring-like structure at the cell division site where it functions as a scaffold for the molecular machinery that performs cell division. However, the genome of the anammox bacterium 'Candidatus Kuenenia stuttgartiensis' does not encode ftsZ. Genomic analysis of open reading frames with potential GTPase activity indicated a possible novel cell division ring gene: kustd1438, which was unrelated to ftsZ. Immunogold localization specifically localized kustd1438 to the cell division ring. Genomic analyses of other members of the phyla Planctomycetes and Chlamydiae revealed no putative functional homologues of kustd1438, suggesting that it is specific to anammox bacteria. Electron tomography also revealed that the bacterial organelle was elongated along with the rest of the cell and divided equally among daughter cells during the cell division process.
Keywords
Anaerobiosis, Bacteria/metabolism, Bacteria/ultrastructure, Bacterial Physiological Phenomena, Bacterial Proteins/metabolism, Cell Division, Electron Microscope Tomography, Gene Order, Genes, Bacterial, Macromolecular Substances, Microscopy, Electron, Transmission, Microscopy, Immunoelectron, Organelles/metabolism, Organelles/ultrastructure, Oxidation-Reduction, Quaternary Ammonium Compounds/metabolism
Pubmed
Web of science
Create date
27/02/2012 10:39
Last modification date
20/08/2019 13:15
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