Fructose and dietary thermogenesis

Details

Serval ID
serval:BIB_30192132822F
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Fructose and dietary thermogenesis
Journal
American Journal of Clinical Nutrition
Author(s)
Tappy  L., Jequier  E.
ISSN
0002-9165 (Print)
Publication state
Published
Issued date
11/1993
Volume
58
Number
5 Suppl
Pages
766S-770S
Notes
Journal Article
Review --- Old month value: Nov
Abstract
Ingestion of nutrients increases energy expenditure above basal metabolic rate. Thermogenesis of carbohydrate comprises two distinct components: an obligatory component, which corresponds to the energy cost of carbohydrate absorption, processing, and storage; and a facultative component, which appears to be related with a carbohydrate-induced stimulation of the sympathetic nervous system, and can be inhibited by beta-adrenergic antagonists. Fructose ingestion induces a greater thermogenesis than does glucose. This can be explained by the hydrolysis of 3.5-4.5 mol ATP/mol fructose stored as glycogen, vs 2.5 mol ATP/mol glucose stored. Therefore the large thermogenesis of fructose corresponds essentially to an increase in obligatory thermogenesis. Obese individuals and obese patients with non-insulin-dependent diabetes mellitus commonly have a decrease in glucose-induced thermogenesis. These individuals in contrast display a normal thermogenesis after ingestion of fructose. This may be explained by the fact that the initial hepatic fructose metabolism is independent of insulin. This observation indicates that insulin resistance is likely to play an important role in the decreased glucose-induced thermogenesis of these individuals.
Keywords
Body Temperature Regulation/*physiology Dietary Carbohydrates/administration & dosage/*metabolism Dietary Fats/metabolism Dietary Proteins/metabolism Energy Metabolism/physiology Fructose/administration & dosage/*metabolism Humans Insulin Resistance/physiology
Pubmed
Web of science
Create date
24/01/2008 14:37
Last modification date
20/08/2019 14:14
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