Influence of sleep stage and wakefulness on spectral EEG activity and heart rate variations around periodic leg movements.

Details

Serval ID
serval:BIB_2F92905939B9
Type
Article: article from journal or magazin.
Collection
Publications
Title
Influence of sleep stage and wakefulness on spectral EEG activity and heart rate variations around periodic leg movements.
Journal
Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology
Author(s)
Lavoie S., de Bilbao F., Haba-Rubio J., Ibanez V., Sforza E.
ISSN
1388-2457 (Print)
ISSN-L
1388-2457
Publication state
Published
Issued date
2004
Volume
115
Number
10
Pages
2236-2246
Language
english
Notes
Publication types: Clinical Trial ; Journal Article
Publication Status: ppublish
Abstract
OBJECTIVE: Typical changes in spectral electroencephalographic (EEG) activity and heart rate (HR) have been described in periodic leg movements (PLM) associated with or without microarousals (MA). We aimed to determine the effects of sleep stage and wakefulness on these responses to ascertain whether a common pattern of EEG and HR activation takes place.
METHODS: The time course of EEG spectral activity and HR variability associated with PLM was analysed in 13 patients during light NREM sleep, rapid-eye-movement (REM) sleep and wakefulness. The same analysis was also conducted for PLM without MA occurring in stage 2.
RESULTS: A significant EEG and electrocardiogram (ECG) activation was found associated with PLM during sleep, but not during wakefulness. While in light NREM sleep, an increase in delta and theta bands was detected before the PLM onset, in REM sleep the EEG activation occurred simultaneously with the PLM onset. Moreover, during stage 1 and REM sleep, alpha and fast frequencies tended to remain sustained after the PLM onset. In contrast, during wakefulness, a small and not significant increase in cerebral activity was present, starting at the PLM onset and persisting in the post-movement period. A typical pattern of cardiac response was present during NREM and REM sleep, the autonomic activation being lesser and prolonged during wakefulness.
CONCLUSIONS: We conclude that the EEG and HR responses to PLM differ between sleep stages and wakefulness with lesser changes found during wakefulness.
SIGNIFICANCE: These findings suggest that specific sleep state-dependent mechanisms may underlie the occurrence of PLM.
Keywords
Adult, Aged, Alpha Rhythm, Arousal/physiology, Delta Rhythm, Electroencephalography, Female, Heart Rate/physiology, Humans, Leg/physiology, Male, Middle Aged, Movement/physiology, Polysomnography, Sleep Stages/physiology, Sleep, REM/physiology, Theta Rhythm, Wakefulness/physiology
Pubmed
Create date
24/04/2016 9:58
Last modification date
19/11/2019 6:26
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