Systemic mastocytosis following a malignant ovarian germ cell tumour.

Details

Serval ID
serval:BIB_2F5E7BD3663D
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Systemic mastocytosis following a malignant ovarian germ cell tumour.
Journal
Histopathology
Author(s)
Delacrétaz F., Stalder M., Meugé-Moraw C., Schmidt P.M., Joris F., Kurt A.M., De Werra P.
ISSN
0309-0167
Publication state
Published
Issued date
1997
Peer-reviewed
Oui
Volume
30
Number
6
Pages
582-4
Language
english
Notes
Publication types: Case Reports ; Journal Article - Publication Status: ppublish
Abstract
Cases of mediastinal germ cell tumours associated with haematological disorders (two cases of systemic mastocytosis included) have been reported previously. This combination is more frequent than would be expected by chance alone. We report the case of a 30-year-old woman, who presented with a systemic mastocytosis following a malignant ovarian germ cell tumour which was treated by chemo- and radiotherapy. The patient predominantly complained of skeletal pains, which led to an erroneous radiological diagnosis of fibrous dysplasia for years. An aggressive variant of systemic mastocytosis was diagnosed on bone marrow examination. Systemic mastocytosis was confirmed by splenectomy, liver biopsy and finally autopsy. The present case is unique because of the ovarian location of the germ cell tumour. We suggest our observation could be related to the broad group of haematological malignancies associated with germ cell tumours.
Keywords
Adolescent, Biopsy, Fatal Outcome, Female, Femur, Fibrous Dysplasia, Polyostotic, Germinoma, Humans, Mastocytosis, Ovarian Neoplasms, Spleen
Pubmed
Web of science
Create date
29/01/2008 18:34
Last modification date
20/08/2019 13:13
Usage data