Is lean body mass decreased after obesity treatment by adjustable gastric banding?

Details

Serval ID
serval:BIB_2F5C2522C050
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Is lean body mass decreased after obesity treatment by adjustable gastric banding?
Journal
Obesity Surgery
Author(s)
Coupaye M., Bouillot J.L., Poitou C., Schutz Y., Basdevant A., Oppert J.M.
ISSN
0960-8923 (Print)
ISSN-L
0960-8923
Publication state
Published
Issued date
04/2007
Peer-reviewed
Oui
Volume
17
Number
4
Pages
427-433
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
BACKGROUND: There is concern that surgically-induced weight loss in obese subjects is associated with a disproportionate decrease in lean body mass (LBM) and in skeletal muscle mass (SMM), a major constituent of LBM. To address this issue, 1) we measured total and regional body composition following gastric banding in a group of obese subjects, and 2) we compared these data to those of a non-surgical control group of similar age and body size.
METHODS: Body composition was assessed by dual-energy X-ray absorptiometry (DEXA) before and after laparoscopic adjustable silicone gastric banding (LAGB) in 32 women (after 1 year: age 43.7+/-8.4 years, BMI 36.4+/-5.9 kg/m2, mean+/-SD), and in 117 control women (age 44.5+/-7.5 years; BMI 36.7+/-5.5 kg/m2) referred for non-surgical weight management, prior to weight loss. SMM was estimated using a published equation based on LBM of the extremities (appendicular LBM).
RESULTS: 1 year after LAGB, body weight loss (-23.7+/-11.6 kg, P<10(-6)) was mainly due to decreased fat mass (-21.2+/-11.2 kg, P<10(-6)), and total LBM was modestly, although significantly, decreased (-2.1+/-4.2 kg, P=0.01). Appendicular LBM (-0.7+/-2.7 kg) and total SMM (-0.9+/-3.0 kg) were not significantly modified. None of the body composition variables was significantly decreased in weight-reduced subjects compared to the control group, especially appendicular LBM and total SMM.
CONCLUSIONS: Results provide no evidence for a decrease in appendicular LBM and total SMM with weight loss following LAGB. Follow-up of these obese patients revealed a very favorable pattern of change in total and regional body composition, with preservation of muscle mass.
Keywords
Absorptiometry, Photon, Adult, Body Composition, Body Mass Index, Case-Control Studies, Female, Follow-Up Studies, Gastroplasty, Humans, Male, Middle Aged, Obesity/surgery, Weight Loss
Pubmed
Web of science
Create date
21/01/2008 13:08
Last modification date
20/08/2019 13:13
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