Artificially selecting microbial communities: If we can breed dogs, why not microbiomes?

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Version: Final published version
License: CC BY 4.0
Serval ID
serval:BIB_2EED4F6F5A44
Type
Article: article from journal or magazin.
Publication sub-type
Vulgarization: article from the non-specific scientific community or a vulgarization of a scientifical paper.
Collection
Publications
Institution
Title
Artificially selecting microbial communities: If we can breed dogs, why not microbiomes?
Journal
PLoS biology
Author(s)
Arias-Sánchez F.I., Vessman B., Mitri S.
ISSN
1545-7885 (Electronic)
ISSN-L
1544-9173
Publication state
Published
Issued date
08/2019
Peer-reviewed
Oui
Volume
17
Number
8
Pages
e3000356
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Comment
Publication Status: epublish
Abstract
Natural microbial communities perform many functions that are crucial for human well-being. Yet we have very little control over them, and we do not know how to optimize their functioning. One idea is to breed microbial communities as we breed dogs: by comparing a set of microbiomes and allowing the best-performing ones to generate new communities, and so on. Although this idea seems simple, designing such a selection experiment brings with it many decisions with surprising outcomes. Xie and colleagues developed a computational model that reveals this complexity and shows how different experimental design decisions can impact the success of such an experiment.
Keywords
Animals, Breeding, Dogs, Humans, Microbiota
Pubmed
Web of science
Open Access
Yes
Create date
17/09/2019 21:52
Last modification date
15/01/2021 8:08
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