Pleiotropy in the melanocortin system, coloration and behavioural syndromes.

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State: Public
Version: author
Serval ID
serval:BIB_2EC1D375BAD5
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Pleiotropy in the melanocortin system, coloration and behavioural syndromes.
Journal
Trends in Ecology and Evolution
Author(s)
Ducrest A.L., Keller L., Roulin A.
ISSN
0169-5347[print], 0169-5347[linking]
Publication state
Published
Issued date
2008
Peer-reviewed
Oui
Volume
23
Number
9
Pages
502-510
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Review Publication Status: ppublish
Abstract
In vertebrates, melanin-based coloration is often associated with variation in physiological and behavioural traits. We propose that this association stems from pleiotropic effects of the genes regulating the synthesis of brown to black eumelanin. The most important regulators are the melanocortin 1 receptor and its ligands, the melanocortin agonists and the agouti-signalling protein antagonist. On the basis of the physiological and behavioural functions of the melanocortins, we predict five categories of traits correlated with melanin-based coloration. A review of the literature indeed reveals that, as predicted, darker wild vertebrates are more aggressive, sexually active and resistant to stress than lighter individuals. Pleiotropic effects of the melanocortins might thus account for the widespread covariance between melanin-based coloration and other phenotypic traits in vertebrates.
Keywords
Animals, Behavior, Animal/physiology, Melanins/metabolism, Mice, Pigments, Biological/genetics, Pigments, Biological/metabolism, Receptors, Melanocortin/genetics, Strigiformes/genetics, Strigiformes/metabolism
Pubmed
Web of science
Open Access
Yes
Create date
11/06/2008 8:18
Last modification date
20/08/2019 14:13
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