Lipedema: A Call to Action!

Details

Serval ID
serval:BIB_2EA7FCA03464
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Lipedema: A Call to Action!
Journal
Obesity
Author(s)
Buso G., Depairon M., Tomson D., Raffoul W., Vettor R., Mazzolai L.
ISSN
1930-739X (Electronic)
ISSN-L
1930-7381
Publication state
Published
Issued date
10/2019
Peer-reviewed
Oui
Volume
27
Number
10
Pages
1567-1576
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
Lipedema is a chronic progressive disease characterized by abnormal fat distribution resulting in disproportionate, painful limbs. It almost exclusively affects women, leading to considerable disability, daily functioning impairment, and psychosocial distress. Literature shows both scarce and conflicting data regarding its prevalence. Lipedema has been considered a rare entity by several authors, though it may be a far more frequent condition than thought. Despite the clinical impact on women's health, lipedema is in fact mostly unknown, underdiagnosed, and too often misdiagnosed with other similarly presenting diseases. Polygenic susceptibility combined with hormonal, microvascular, and lymphatic disorders may be partly responsible for its development. Furthermore, consistent information on lipedema pathophysiology is still lacking, and an etiological treatment is not yet available. Weight loss measures exhibit minimal effect on the abnormal body fat distribution, resulting in eating disorders, increased obesity risk, depression, and other psychological complaints. Surgical techniques, such as liposuction and excisional lipectomy, represent therapeutic options in selected cases. This review aims to outline current evidence regarding lipedema epidemiology, pathophysiology, clinical presentation, differential diagnosis, and management. Increased awareness and a better understanding of its clinical presentation and pathophysiology are warranted to enable clinicians to diagnose and treat affected patients at an earlier stage.
Keywords
Body Fat Distribution, Diagnosis, Differential, Female, Humans, Lipectomy/methods, Lipectomy/standards, Lipedema/diagnosis, Lipedema/epidemiology, Lipedema/etiology, Lipedema/therapy, Male, Obesity/complications, Obesity/diagnosis, Obesity/epidemiology, Obesity/therapy
Pubmed
Web of science
Open Access
Yes
Create date
24/09/2019 11:47
Last modification date
25/11/2020 6:26
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